Preventing cell damage: Working principle of proton-activated chloride channels revealed

A research team led by Prof. Seo Byeong-Chang of the Department of Brain Sciences at DGIST has made the world's first discovery of how proton-activated chloride (PAC) channels—which play an important role in protecting cells in our bodies—work. PAC channels are important mediators of cell damage caused by tissue acidification, and by unraveling the mystery of how they are activated, the research team has opened up a new road for treating cancer and brain diseases.