Live-cell imaging under centrifugation: New method measure the forces that keep the nuclei of living cells centered

Using two specialized microscopes invented at the Marine Biological Laboratory (MBL), a team of researchers from Japan and the MBL have developed a new method to measure the forces that keep the nucleus centered within a living cell. The experiments also provided important new clues about the properties of cellular cytoplasm and the mechanisms of organelle motion within cells. The work appears in Proceedings of the National Academy of Sciences.