Diverse pathways to longevity in mammals uncovered

Researchers from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, have discovered gene expression signatures of longevity across 41 mammalian species and compared them with biomarkers of lifespan-extending interventions and mammalian aging. This work revealed distinct and universal molecular mechanisms of longevity and provided new ways to identify lifespan-extending interventions. Results are published in Cell.