A huge fire has engulfed a tower block in Latimer Road, West London.
Eyewitnesses claim people are trapped in their homes.
According to reports, the fire at Grenfell Tower on the Lancaster West Estate was reported at 01:16 BST and about 200 firefighters are tackling the blaze.
The Met Police said people were being treated for “a range of injuries”.
Forty fire engines have been sent to the tower, and Mayor of London Sadiq Khan said a “major incident” had been declared.
Eyewitnesses said they could see lights – thought to be mobile phones or torches – flashing at the top of the block of flats, which people say is close to burning through.
Reports said the tower could be seen burning from miles away and added that building was burning out of control, from the tenth floor onwards.
London Ambulance Service medics specially trained in life-saving medical care in hazardous environments have also been sent to the fire.
London Underground said the Hammersmith and City and Circle lines have been closed between Edgware Road and Hammersmith because of the fire.
According Kensington and Chelsea Council, the tower block contains 120 flats and is 24 storeys high.
It is managed by the Kensington and Chelsea Tenant Management Organisation (KCTMO) on behalf of the council.