Roger Federer

Roger Federer cut down big-serving American John Isner in straight sets at the US Open on Monday to claim an accustomed grand slam quarter-finals spot at Flushing Meadows.

The Swiss second seed, winner of a record 17 grand slam titles, beat 13th seed Isner 7-6 (0), 7-6 (6), 7-5 to set up a last eight clash against 12th-seeded Frenchman Richard Gasquet, who ousted sixth-seeded Czech Tomas Berdych in four sets.

The world number two will be contesting his 46th grand slam quarter-final.

Federer, who never lost his serve, held his own from the service line to thwart Isner and used his returning skills to derail a pair of long streaks enjoyed by the American.

Federer, 34, closed out the two hour, 39 minute fourth-round match by breaking the 6ft 10in Isner’s serve, ending the American’s string of 108 consecutive service holds at the US Open, dating back to the beginning of last year’s championship.

His perfect scoreline in the opening set tiebreak snapped an even longer Isner streak.

In 429 tiebreakers played by Isner, he had never dropped one 7-0.

“Seven-love obviously is a pretty good score against John,” said Federer.

Murray beaten

Andy Murray suffered his earliest Grand Slam exit for five years as he lost a gruelling fourth-round contest against 15th seed Kevin Anderson.

The South African won 7-6 (7-5) 6-3 6-7 (2-7) 7-6 (7-0) in four hours and 18 minutes to reach a first major quarter-final, where he faces Stan Wawrinka.

It is the first time since the 2010 US Open that Murray has lost before the quarter-finals of a Grand Slam.